Explore our resources to discover what you can do about improving diagnosis of FH and the importance of early detection for its rare, homozygous form, HoFH.
Pediatric lipid screening rates and awareness of FH are limited in the US2
Although HeFH occurs in 1 in ~250 individuals and HoFH in 1 in ~250,000 individuals, the true prevalence of FH may not be fully understood, as both forms may be asymptomatic.1,2,4,5,7 Discover the actionable steps to raise awareness of FH and its rare form, HoFH.
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Early pediatric lipid screening supports early diagnosis and intervention in FH5
By initiating lipid screening at a young age, HCPs can proactively identify children who may be at risk for FH or other lipid disorders.5 Explore ways to implement pediatric lipid screening in practice.
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Early diagnosis and intervention can change the trajectory of FH5
Identification of FH at an early stage helps optimize patient care.5 Delve deeper into FH to support early diagnosis.
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Making sense of homozygous FH guidelines
Delayed FH diagnosis can increase the risk of complications8
If left undetected and untreated, FH could lead to myocardial infarctions by age 40 in those with HeFH,9 and premature atherosclerotic cardiovascular disease in the first decade of life in those with HoFH.10,11
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References
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Gidding SS et al. Circulation 2015;132:2167–2192.
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de Ferranti SD et al. J Pediatr 2017;185:99–105.
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Banda JM et al. NPJ Digit Med 2019;2:23.
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Raal FJ et al. Atherosclerosis 2018;277:483–492.
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McGowan MP et al. J Am Heart Assoc 2019;8:e013225.
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Berger JH et al. J Am Heart Assoc 2022;11:e024197.
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Cuchel M et al. Eur Heart J 2023;44:2277-2291.
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Nordestgaard et al. Eur Heart J 2013;34:3478-90a.
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Luirink IK et al. N Engl J Med 2019;381:1547-1556.
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Cuchel M et al. J Am Heart Assoc 2023;12:e029175.
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Family Heart Foundation. https://familyheart.org/new-research-children-and-hofh (accessed February 2024).